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FAQ

FAQ

General
What is a biomarker?
How is a biomarker used?

MESOMARK®
What is the MESOMARK test?
What is a Humanitarian Use Device (HUD)?
How is the MESOMARK test performed?
What do the MESOMARK test results mean?
How do I get the MESOMARK test?
Where can I obtain additional information about the MESOMARK test?


General

What is a biomarker?
A biomarker is a substance that can often be detected in higher-than-normal amounts in the blood, urine, or body tissues of some patients with certain types of cancer. Biomarkers are produced either by the tumor itself or by the body in response to the presence of cancer or certain benign conditions.

How is a biomarker used?
Measurements of a biomarker can be useful when used along with history, physical examination, and imaging procedures such as x-rays or ultrasound. Biomarkers can be used in a variety of situations to aid in the monitoring of patients.

These include:

  • Detection or screening of cancer
  • Monitoring the effectiveness of therapy during the course of treatment
  • Determining the recurrence of a tumor after primary chemotherapy
  • Differential diagnosis
  • Prognostic or predictive indicators

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MESOMARK

What is the MESOMARK test?
The MESOMARK test is a blood test that measures Soluble Mesothelin-Related Peptide (SMRP) and may aid in the monitoring of patients diagnosed with epithelioid or biphasic mesothelioma. SMRP is a biomarker produced by the mesothelioma cells that can be elevated in the serum of patients suffering from mesothelioma.

What is a Humanitarian Use Device (HUD)?
An HUD is a device that is intended to benefit patients by treating or diagnosing a disease or condition that affects fewer than 4,000 individuals in the United States per year.

How is the MESOMARK test performed?
A blood sample is taken from the patient and then sent to a laboratory for testing to determine the level of SMRP present in the blood. The laboratory determines the amount of SMRP present in the blood by using monoclonal antibodies known to specifically bind to SMRP. By measuring the amount of bound antibodies the laboratory can calculate the amount of SMRP present in the patient's blood.

What do the MESOMARK test results mean?
Physicians should use the MESOMARK test in conjunction with other diagnostic results to make decisions about the monitoring of their patients. Increasing results may be indicative of progressive disease, decreasing results may be indicative of response to therapy and constant results may be associated with stable disease.

How do I get the MESOMARK test ?
Contact your physician to ask him about having the MESOMARK test or contact Fujirebio Diagnostics.

Where can I obtain additional information about the MESOMARK test?
Ask your physician or contact Fujirebio Diagnostics.

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